Background

Percutaneous Coronary Intervention (PCI) has become a cornerstone in the management of coronary artery disease (CAD), offering significant improvements in myocardial perfusion, symptom relief, and survival outcomes. Despite technological advancements and improved procedural techniques, post-PCI clinical outcomes continue to vary based on patient characteristics, comorbidities, and procedural factors.

Objective

To evaluate short-term and intermediate-term clinical outcomes following PCI and identify factors associated with adverse cardiovascular events.

Methods

A prospective observational study was conducted among 450 patients undergoing PCI for coronary artery disease at tertiary cardiac centers. Demographic characteristics, cardiovascular risk factors, procedural details, and post-procedural outcomes were recorded. Major Adverse Cardiovascular Events (MACE) including death, myocardial infarction, target vessel revascularization, and stroke were evaluated during a 12-month follow-up period.

Results

The study included 450 patients with a mean age of 61.4 ± 10.8 years. Successful PCI was achieved in 96.4% of cases. During follow-up, MACE occurred in 9.8% of patients. Hypertension, diabetes mellitus, multivessel disease, and reduced left ventricular ejection fraction were significant predictors of adverse outcomes (p < 0.05). Drug-eluting stents demonstrated superior outcomes compared with bare-metal stents.

Conclusion

PCI remains a highly effective revascularization strategy with favorable clinical outcomes. Careful risk stratification and post-procedural management are essential to minimize adverse cardiovascular events and optimize long-term patient prognosis.