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European Journal of Medical Practitioners
2023, Volume 1, Issue 4 : 1-6
Research Article
Lipid Profile Trends Among High-Risk Cardiovascular Patients: A Longitudinal Observational Study
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1
Department of Cardiology, Heart Care Institute, New York Medical University, USA
2
Department of Internal Medicine, Global Health Research Center, London, United Kingdom
3
Department of Clinical Biochemistry, University Hospital of Medical Sciences, Toronto, Canada
4
Department of Preventive Cardiology, International Cardiovascular Research Institute, Sydney, Australia
5
Department of Epidemiology and Public Health, Boston Research University, USA
Abstract

Background

Dyslipidemia is a major modifiable risk factor for cardiovascular disease (CVD) and contributes significantly to morbidity and mortality worldwide. Monitoring lipid profile trends among high-risk cardiovascular patients is essential for evaluating treatment effectiveness and preventing adverse cardiovascular events.

Objective

To assess lipid profile trends and associated cardiovascular risk factors among high-risk cardiovascular patients receiving routine medical care.

Methods

A longitudinal observational study was conducted among 500 high-risk cardiovascular patients attending tertiary cardiac centers. Lipid profile parameters including total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), and non-HDL cholesterol were evaluated at baseline and during a 12-month follow-up period. Clinical characteristics, medication adherence, and cardiovascular risk factors were analyzed.

Results

Significant reductions in total cholesterol, LDL-C, and triglyceride levels were observed during follow-up (p < 0.001). HDL-C levels demonstrated modest improvement. Patients receiving high-intensity statin therapy showed greater lipid improvement compared with those on moderate-intensity therapy. Diabetes mellitus, obesity, smoking, and poor medication adherence were associated with unfavorable lipid trends.

Conclusion

Lipid profiles improved significantly among high-risk cardiovascular patients receiving evidence-based treatment. Continuous monitoring, lifestyle interventions, and adherence to lipid-lowering therapies remain crucial for reducing cardiovascular risk.

 

 

Keywords
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